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The Environmental Protection Agency (EPA) established a national e-Manifest system for tracking hazardous waste shipments electronically. EPA expects the e-Manifest system will modernize the nation’s cradle-to-grave hazardous waste tracking process while saving valuable time, resources and dollars for industry and states. The e-Manifest system, which was signed into law in 2012 and launches on June 30, 2018, will collect, track and store manifest information in real-time for each waste shipment in a centralized national information hub from the point of collection to its final disposal. The e-Manifest system will be used by generators, transporters and receivers of hazardous waste, as well as state and federal environmental agencies. This regulatory update focuses of what generators can do to prepare for the e-Manifest system launch.