Centers for Disease Control and Prevention Building 401

The projects in Building 401 for the Centers of Disease Control and Prevention (CDC) included the fit-out of the National Center for Infectious Diseases and the Division of Vector-Borne Diseases Replacement Laboratory Facility.


Accommodating Different Bio-Safety Levels

The project spaces include office areas, BSL2 labs and support spaces, and BSL3 labs and support spaces. The subtle differences between BSL2 and 3 spaces, and the need to take those into account, was a cornerstone to WSP USA’s approach.

For instance, BSL2 labs are designed as a combination of open flexible labs and enclosed, dedicated support labs. Support labs are smaller rooms with dedicated equipment layouts tailored to specific functions and include microscopy rooms, reagent rooms, equipment rooms, procedure rooms and tissue culture labs.

The BSL3 laboratories are designed as enclosed areas for concentrated work on agents requiring BSL3 containment. Lab layouts provide space for biosafety cabinets, supporting equipment and a small amount of bench space. The BSL3 laboratories are designed to withstand the physical, thermal, moisture and chemical affects due to normal operating procedures of typical BSL3/BSL3E laboratory spaces including wipe down and chemical disinfecting. All service penetrations into the BSL3 laboratories are sealed.