The new NIH/NIAID intramural high containment defense facility is the first new BSL4, BSL3 and BSL2 building to be constructed at the new National Interagency Bio-defense Campus at Fort Detrick.

 


Location

  • Fort Detrick, Maryland, USA

Sector

Project Status

  • Completed


A First in the World

The key challenge for this project was to provide the first fully integrated advanced medical equipment, clinical support infrastructure, and whole animal imaging core in an ABSL4 and ABSL3 vivarium environment, within a biocontainment facility model – while addressing conflicts between the stringent biosafety requirements of containment barrier design and environmental needs of the finely calibrated scientific equipment.

The facility features highly specialized multiple imaging modalities including MRI, CT-SPECT, CP-PET and X-Ray within a high containment setting. This is the first biocontainment laboratory in the world that fully integrates advanced medical equipment, clinical support infrastructure, and whole animal imaging in a BSL4 and BSL3 vivarium environment. A three-story glass atrium serves as an entry point for all staff and guests, as well as the first layer of security. Beyond the security checkpoint, the laboratory modules and animal holding rooms have been configured to provide isolation of research programs which facilitates preclinical validation of vaccine and therapeutic candidates under Good Laboratory Practices (GLP) conditions. This project had an aggressive front end design of only 8 months from the start of programming to GMP. The schedule was met, and without compromise to the scientific program, or quality due to the team’s expertise in containment design and innovation.